A selective prevention trial using novel pharmacotherapies in an older age cohort at risk for depression

在有抑郁症风险的老年群体中使用新型药物疗法进行选择性预防试验

• 批准号: nhmrc : 1060397
• 负责人: Prof Helen Christensen
• 金额: $ 65.03万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/selective-prevention-trial-risk-depression/454818
• 关键词: selective; prevention; trial; using; novel

The study will examine whether omega-3 fatty acids or antidepressants prevent the onset of depression in a group of older community participants who have previously been identified as being "at risk" of depression. The study will incorporate sophisticated brain scanning methods, as well as tests of brain functioning to determine acute brain changes, reduction in cognitive decline and prevention of depression over a one-year period.

这项研究将研究omega-3脂肪酸或抗抑郁剂是否能预防一组老年社区参与者的抑郁发作，这些参与者之前被确定为抑郁的“风险”。这项研究将纳入复杂的大脑扫描方法，以及大脑功能测试，以确定一年内的急性大脑变化、认知能力下降的减轻和抑郁症的预防。