Serum neurofilament light as a biomarker to improve management of mild traumatic brain injuries

血清神经丝光作为生物标志物改善轻度创伤性脑损伤的治疗

• 批准号: nhmrc : 2002689
• 金额: $ 109.28万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/serum-neurofilament-light-brain-injuries/1779966
• 关键词: Serum; neurofilament; light; biomarker; improve

There is increasing awareness that mild traumatic brain injuries (mTBIs), such as concussions, can lead to persistent or permanent neurological symptoms. Nonetheless, the identification and management of mTBIs remains notoriously difficult. In this proposal, we will assess exactly how a novel blood test can be implemented to assist in mTBI diagnosis, and the identification and management of individuals at risk of suffering persistent or chronic neurological problems.

人们越来越认识到，轻微的创伤性脑损伤（mTBIs），如脑震荡，可导致持续或永久的神经系统症状。尽管如此，mtbi的识别和管理仍然非常困难。在本提案中，我们将准确评估如何实施一种新的血液检查来协助mTBI诊断，以及识别和管理有持续或慢性神经问题风险的个体。