Immune system involvement in skeletal muscle adaptation to contractile activity during human growth

免疫系统参与人体生长过程中骨骼肌对收缩活动的适应

• 批准号: 341353-2007
• 负责人: Timmons, Brian
• 金额: $ 1.82万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=399349
• 关键词: Immune; system; involvement; skeletal; muscle

Most people would agree that exercise for children is essential, but recent statistics tell us that 3 out of 5 Canadian children are not active enough for optimal growth and development, which this proposal defines as the healthy function of tissues (e.g., skeletal muscle). The problems are that 1) the type of exercise that best promotes tissue health in children is unknown, and 2) we do not fully understand the mechanisms that translate exercise into optimal tissue function during human growth. What we do know is that exercise in children activates immune factors with the capacity to benefit tissue function.

大多数人会同意儿童运动是必不可少的，但最近的统计数据告诉我们，五分之三的加拿大儿童不够活跃，无法实现最佳的生长和发育，这项提案将其定义为组织的健康功能（例如，骨骼肌）。 问题在于：1）最能促进儿童组织健康的运动类型尚不清楚，2）我们并不完全了解在人类生长过程中将运动转化为最佳组织功能的机制。 我们所知道的是，儿童运动激活免疫因子，使组织功能受益。