Sleep, telomere length and cardiorespiratory phenotype in 11-12 year old children: Cross-sectional Australian national population based study

11-12 岁儿童的睡眠、端粒长度和心肺表型：澳大利亚全国人口横断面研究

• 批准号: nhmrc : 1115167
• 金额: $ 5.82万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/sleep-telomere-length-based-study/663362
• 关键词: Sleep; telomere; length; cardiorespiratory; phenotype

Telomeres are special areas at the ends of our chromosomes that ‘protect’ our DNA as our body cells divide. With ageing, our telomeres slowly become shorter, but the rate at which this happens varies. My project will investigate the associations between poor sleep duration and quality, increased risk of cardiovascular diseases, poor respiratory health and increased vulnerability to viral infections to shorter telomere length.

端粒是我们染色体末端的特殊区域，在我们的身体细胞分裂时“保护”我们的DNA。随着年龄的增长，我们的端粒慢慢变短，但发生这种情况的速度各不相同。我的项目将调查睡眠时间和质量不佳，心血管疾病风险增加，呼吸系统健康状况不佳以及对病毒感染的脆弱性增加与端粒长度较短之间的关系。