The interactions of drugs with biological and liposomal membranes

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The proposed work aims at establishing quantitative biophysical rules describing the interaction of drugs and other small molecules with biological and liposomal membranes. These are of fundamental interest since virtually all drugs have to interact with membranes; they may bind to membrane receptors, act by changing membrane properties, or need to cross membranes to reach their target. Furthermore, artificial membranes (liposomes) are loaded with drugs for targeted drug delivery and optimized release.