Steroid-Reducing Options for ReLapsING PMR (STERLING-PMR): a pragmatic, randomised trial to compare the clinical and cost-effectiveness of adding immunosuppression to steroid-tapering treatment for patients with relapsing PMR, versus steroid-tapering

ReLapsING PMR 的类固醇减少方案 (STERLING-PMR)：一项务实的随机试验，旨在比较在复发性 PMR 患者的类固醇逐渐减少治疗中添加免疫抑制与类固醇逐渐减少的临床和成本效益

• 批准号: nhmrc : 2006408
• 金额: $ 82.37万
• 依托单位国家: 澳大利亚
• 项目类别: International Collaborations
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/steroid-reducing-options-steroid-tapering/1780866
• 关键词: Steroid; Reducing; Options; ReLapsING; PMR

Polymyalgia rheumatica (PMR) is a common inflammatory disease of older people, treated with prednisolone (steroid tablet). About 50% will relapse and often suffer from steroid side effects (eg diabetes, bone fracture). This study will determine whether an extra treatment can reduce prednisolone use in people with relapsing PMR; and improve quality of life. The study will include participants in UK and Australia and provide a unique opportunity for further research in this under-researched area.

风湿性多肌痛（PMR）是老年人常见的炎症性疾病，用泼尼松龙（类固醇片剂）治疗。约50%会复发，并经常遭受类固醇副作用（如糖尿病，骨折）。这项研究将确定额外的治疗是否可以减少复发性PMR患者使用泼尼松龙，并改善生活质量。该研究将包括英国和澳大利亚的参与者，并为这一研究不足的领域提供进一步研究的独特机会。