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Steroid-Reducing Options for ReLapsING PMR (STERLING-PMR): a pragmatic, randomised trial to compare the clinical and cost-effectiveness of adding immunosuppression to steroid-tapering treatment for patients with relapsing PMR, versus steroid-tapering

Steroid-Reducing Options for ReLapsING PMR (STERLING-PMR): a pragmatic, randomised trial to compare the clinical and cost-effectiveness of adding immunosuppression to steroid-tapering treatment for patients with relapsing PMR, versus steroid-tapering
ReLapsING PMR 的类固醇减少方案 (STERLING-PMR):一项务实的随机试验,旨在比较在复发性 PMR 患者的类固醇逐渐减少治疗中添加免疫抑制与类固醇逐渐减少的临床和成本效益
批准号:
nhmrc : 2006408
负责人:
金额:
$82.37万
依托单位:
依托单位国家:
澳大利亚
项目类别:
International Collaborations
财政年份:
2022
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2022-01-01 至 2025-12-31

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英文摘要
Polymyalgia rheumatica (PMR) is a common inflammatory disease of older people, treated with prednisolone (steroid tablet). About 50% will relapse and often suffer from steroid side effects (eg diabetes, bone fracture). This study will determine whether an extra treatment can reduce prednisolone use in people with relapsing PMR; and improve quality of life. The study will include participants in UK and Australia and provide a unique opportunity for further research in this under-researched area.
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