Strain-level characterisation and visualisation of the mucosal microbial communities associated with Inflammatory Bowel Disease (IBD) for the development of novel biotherapeutics

与炎症性肠病 (IBD) 相关的粘膜微生物群落的菌株水平表征和可视化，用于开发新型生物治疗药物

• 批准号: nhmrc : 2003385
• 金额: $ 118.19万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/strain-level-characterisation-novel-biotherapeutics/1780122
• 关键词: Strain; level; characterisation; visualisation; mucosal

Australia has one of the highest incidence rates in the world of Inflammatory Bowel Disease (IBD), a debilitating inflammatory condition of the gastrointestinal tract. Cutting-edge molecular and visualisation technologies will be used to examine the role of the gut microbiome in IBD, and identify specific members of this community to be used as new therapies to suppress inflammation and improve outcomes for patients with IBD.

澳大利亚是世界上炎症性肠病（IBD）发病率最高的国家之一，IBD是一种使胃肠道衰弱的炎症性疾病。尖端的分子和可视化技术将用于研究肠道微生物组在IBD中的作用，并确定该群体的特定成员，以用作抑制炎症和改善IBD患者预后的新疗法。