Structural and functional analysis of a cancer-linked co-regulator complex

癌症相关协同调节复合物的结构和功能分析

• 批准号: nhmrc : 1063301
• 负责人: Dr Daniel Ryan
• 金额: $ 48.65万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structural-functional-analysis-regulator-complex/455050
• 关键词: Structural; functional; analysis; cancer; linked

We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.

我们试图了解基因在我们一生中开启和关闭的机制。许多多组分蛋白质机器参与了这一过程，但它们的组成和作用机制尚不清楚。我们将研究其中一种与癌症密切相关的机器的结构和功能。