Structural and functional studies of the human IL-3 receptor

人类 IL-3 受体的结构和功能研究

• 批准号: nhmrc : 1036849
• 负责人: Dr Urmi Dhagat
• 金额: $ 20.53万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structural-functional-studies-3-receptor/111035
• 关键词: Structural; functional; studies; human; IL

This proposal will study a protein hormone that is implicated in blood cell cancers and inflammatory diseases and for which current treatments are inadequate. We will determine how the hormone receptor becomes activated, identify and characterise new agents that block this activation. This information will help in the development of new and highly specific drugs for use in certain cancers in inflammatory diseases.

这项提案将研究一种与血细胞癌和炎症性疾病有关的蛋白质激素，目前的治疗方法还不够。我们将确定激素受体是如何被激活的，识别和识别阻止这种激活的新药物。这些信息将有助于开发新的和高度特异性的药物，用于某些炎症性疾病中的癌症。