Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi

酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用

基本信息

  • 批准号:
    364356-2008
  • 负责人:
  • 金额:
    $ 2.91万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
  • 财政年份:
    2008
  • 资助国家:
    加拿大
  • 起止时间:
    2008-01-01 至 2009-12-31
  • 项目状态:
    已结题

项目摘要

Dutch elm disease (DED) is the most destructive disease of elms. It has been estimated that, during the last 100 years, over one billion mature elms were killed by two successive pandemics of DED caused by two microscopic fungi called Ophiostoma ulmi and O. novo-ulmi. Our ongoing research suggests that an Ophiostoma gene (called Omp2) coding for a high affinity ammonium transporter is important for the virulence of the DED pathogens towards elms. We intend to clarify the role of Omp2 in pathogenesis. In particular, we will verify the hypothesis that the action of Omp2 stems from its effect on the regulation of yeast and mycelium forms of the DED fungi in the presence of low concentrations of ammonium. We further propose to analyse two additional genes which may be involved in other regulatory pathways for fungal growth, as suggested by the recovery of O. novo-ulmi mutants with impaired yeast or mycelial development. The short-term benefit of this project is a better understanding of how the DED fungi develop in elms and eventually kill them. Anticipated long-term benefits are the identification of fungal targets for the development of efficient and environmentally acceptable control methods to save the elms.
荷兰榆树病(Dutch Elm Disease,DED)是榆树的一种重要病害。据估计,在过去的100年里,超过10亿的成熟榆树被两种叫做Ophiostoma ulmi和O.新乌尔米。我们正在进行的研究表明,Ophiostoma基因(称为Omp 2)编码的高亲和力铵转运蛋白是重要的DED病原体对榆树的毒力。我们的目的是阐明Omp 2在发病机制中的作用。特别是,我们将验证的假设,Omp 2的行动源于其对酵母和菌丝体形式的DED真菌在低浓度的铵的存在下的调节的效果。我们进一步建议分析两个额外的基因,它们可能参与真菌生长的其他调控途径,如O。具有受损的酵母或菌丝体发育的新榆突变体。该项目的短期效益是更好地了解DED真菌如何在榆树中发展并最终杀死它们。预期的长期效益是确定真菌目标,以开发有效和环境可接受的控制方法,以拯救榆树。

项目成果

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会议论文数量(0)
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Bernier, Louis其他文献

Characterization of three DNA transposons in the Dutch elm disease fungi and evidence of repeat-induced point (RIP) mutations
  • DOI:
    10.1016/j.fgb.2006.11.016
  • 发表时间:
    2007-05-01
  • 期刊:
  • 影响因子:
    3
  • 作者:
    Bouvet, Guillaume F.;Jacobi, Volker;Bernier, Louis
  • 通讯作者:
    Bernier, Louis
Identification and monitoring of Ulmus americana transcripts during in vitro interactions with the Dutch elm disease pathogen Ophiostoma novo-ulmi
Variability of nuclear SSU-rDNA group introns within Septoria species:: Incongruence with host sequence phylogenies
  • DOI:
    10.1007/s00239-005-0309-7
  • 发表时间:
    2007-05-01
  • 期刊:
  • 影响因子:
    3.9
  • 作者:
    Feau, Nicolas;Hamelin, Richard C.;Bernier, Louis
  • 通讯作者:
    Bernier, Louis
Complexities underlying the breeding and deployment of Dutch elm disease resistant elms.
  • DOI:
    10.1007/s11056-021-09865-y
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    Martin, Juan A.;Dominguez, Jorge;Solla, Alejandro;Brasier, Clive M.;Webber, Joan F.;Santini, Alberto;Martinez-Arias, Clara;Bernier, Louis;Gil, Luis
  • 通讯作者:
    Gil, Luis
Genome-wide analysis of parasitic fitness traits in a non-model tree pathogen

Bernier, Louis的其他文献

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{{ truncateString('Bernier, Louis', 18)}}的其他基金

Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2022
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2021
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2020
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2019
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2018
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
A genome-wide analysis of parasitic fitness in the Dutch elm disease fungus Ophiostoma novo-ulmi
荷兰榆树病真菌 Ophiostoma novo-ulmi 寄生适应性的全基因组分析
  • 批准号:
    105519-2013
  • 财政年份:
    2017
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
A genome-wide analysis of parasitic fitness in the Dutch elm disease fungus Ophiostoma novo-ulmi
荷兰榆树病真菌 Ophiostoma novo-ulmi 寄生适应性的全基因组分析
  • 批准号:
    105519-2013
  • 财政年份:
    2015
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
A genome-wide analysis of parasitic fitness in the Dutch elm disease fungus Ophiostoma novo-ulmi
荷兰榆树病真菌 Ophiostoma novo-ulmi 寄生适应性的全基因组分析
  • 批准号:
    105519-2013
  • 财政年份:
    2014
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
A genome-wide analysis of parasitic fitness in the Dutch elm disease fungus Ophiostoma novo-ulmi
荷兰榆树病真菌 Ophiostoma novo-ulmi 寄生适应性的全基因组分析
  • 批准号:
    105519-2013
  • 财政年份:
    2013
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    105519-2008
  • 财政年份:
    2012
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual

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  • 批准号:
    30370736
  • 批准年份:
    2003
  • 资助金额:
    20.0 万元
  • 项目类别:
    面上项目

相似海外基金

Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2022
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2021
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2020
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2019
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Yeast-mycelium dimorphism in the Dutch elm disease fungi and its contribution to pathogenicity and overall fitness
荷兰榆树病真菌中的酵母菌丝体二态性及其对致病性和整体适应性的贡献
  • 批准号:
    RGPIN-2018-06607
  • 财政年份:
    2018
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    105519-2008
  • 财政年份:
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  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    105519-2008
  • 财政年份:
    2011
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    364356-2008
  • 财政年份:
    2010
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    105519-2008
  • 财政年份:
    2010
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
Role of yeast-mycelium transition in the pathogenicity of the Dutch elm disease fungus Ophiostoma novo-ulmi
酵母菌丝体转变在荷兰榆树病真菌 Ophiostoma novo-ulmi 致病性中的作用
  • 批准号:
    105519-2008
  • 财政年份:
    2009
  • 资助金额:
    $ 2.91万
  • 项目类别:
    Discovery Grants Program - Individual
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