Plasmonic nanoparticles for probing and perturbing the spatial organisation of membrane proteins

用于探测和扰动膜蛋白空间组织的等离子体纳米粒子

• 批准号: DP130101475
• 负责人: Prof Andrew Clayton
• 金额: $ 23.2万
• 依托单位: Swinburne University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130101475
• 关键词: Plasmonic; nanoparticles; probing; perturbing; spatial

Receptors on the surface of cells provide vital functions and represent a large fraction of drug targets. It is believed that the spatial organisation of receptors can effect their function. This project will test this hypothesis by combining nanotechnology with biophysics to watch and manipulate the spatial organisation of receptors.

细胞表面的受体提供重要功能并代表大部分药物靶点。人们相信受体的空间组织可以影响它们的功能。该项目将通过将纳米技术与生物物理学相结合来观察和操纵受体的空间组织来测试这一假设。