Instrument for characterization of plymers and solute release kinetics
Instrument for characterization of plymers and solute release kinetics
批准号:
374799-2009
负责人:
Wu, XiaoYu(Shirley)
金额:
$5.51万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31
中文摘要
生物相容聚合物已被广泛用于制造各种先进的药物,如每天一次的降压药片,它比传统药物提供更有效的治疗和更低的副作用。聚合物的性质,如分子质量和溶解速度,决定了药物的起效时间和起效速度,从而影响到这类药物的治疗效果。与小分子不同,在一次反应中制备的聚合物可能具有不同的分子量,一些聚合物在使用过程中会降解,从而控制药物中治疗剂的释放速度。
英文摘要
Biocompatible polymers have been widely used to make various advanced medications such as once daily blood-pressure-controlling pills that provide more effective treatment with lower side effects than conventional medications. The properties of polymers such as molecular weight and dissolving rate determine when and how fast the medicine will take effect thus affecting the therapeutic benefit of such medications. Unlike small molecules, polymers prepared in one reaction can have different molecular weights, and some polymers degrade during application thus controlling the release rate of therapeutic agents from the medications.
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会议论文
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2010
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2009
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
-
项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2008
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Kinetics and mechanism of solute transport in heterogeneous polymer systems
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批准号:170460-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2007
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
海外基金