T Cells: Their Impact on HIV Evolution and Their Regulation in Influenza

T 细胞：它们对 HIV 进化的影响及其对流感的调节

• 批准号: nhmrc : 567054
• 负责人: Dr Vivienne Peut
• 金额: $ 22.57万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/t-cells-impact-regulation-influenza/116036
• 关键词: Cells; Their; Impact; HIV; Evolution

The T cells of our immune system are critical defenders against viral infection. It is vitally important to understand what stimulates these cells so we can better target them against globally important viruses, such as HIV and influenza - infections that kill millions per year. We need to understand what genes in the T cell turns them into effective killers and which part of these viruses elicits the most effective T cell response. We can use this knowledge for vaccine development.

我们免疫系统的T细胞是抵抗病毒感染的关键防御者。了解是什么刺激了这些细胞至关重要，这样我们就可以更好地靶向它们对抗全球重要的病毒，如艾滋病毒和流感-每年造成数百万人死亡的感染。我们需要了解T细胞中的哪些基因使它们成为有效的杀手，以及这些病毒的哪一部分激发了最有效的T细胞反应。我们可以利用这些知识来开发疫苗。