Targeted redox therapy for photoageing prevention and treatment

用于光老化预防和治疗的靶向氧化还原疗法

• 批准号: nhmrc : 1008739
• 负责人: Prof Michael Roberts
• 金额: $ 37.53万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeted-redox-therapy-prevention-treatment/109337
• 关键词: Targeted; redox; therapy; photoageing; prevention

Our goal is to target natural reduction/oxidation (redox) modifiers, i.e. niacin and sulforaphane, to the skin deeper layers to treat photoageing. Both drugs have been separately shown to prevent UV induced skin cancer. The outcomes of this project will be safer and more effective prevention and treatment of sun damaged skin. This project can provide health benefits to Australians from improved treatment of sun damage, and economic benefits to the nation.

我们的目标是将天然还原/氧化（氧化还原）调节剂（即烟酸和萝卜硫素）靶向皮肤深层，以治疗光老化。这两种药物已分别被证明可以预防紫外线引起的皮肤癌。该项目的成果将是更安全、更有效地预防和治疗晒伤皮肤。该项目可以通过改进对阳光损伤的治疗来为澳大利亚人带来健康益处，并为国家带来经济效益。