Targeting critical nodes on the IGF1-PI3K pathway to improve function of the failing heart
Targeting critical nodes on the IGF1-PI3K pathway to improve function of the failing heart
批准号:
nhmrc : 526647
负责人:
A/Pr Elizabeth Woodcock
金额:
$34.2万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Heart failure is a major clinical problem which is becoming worse as our population grows older and comorbidities such as obesity and diabetes become more prevalent. Current heart failure therapeutics largely delay disease progression. This research proposal focuses on strategies designed to improve function of the failing heart, as opposed to simply delaying disease progression. This approach will lead to the development of new therapeutics.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Identification of novel targets for treatment of heart failure
-
批准号:nhmrc : 1022678
-
项目类别:Project Grants
-
资助金额:$32.46万
-
财政年份:2012
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Phospholipase Cbeta 1b, a target to limit atrial dilatation
-
批准号:nhmrc : 1002328
-
项目类别:Project Grants
-
资助金额:$36.33万
-
财政年份:2011
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
SHANK3 as a target to reduce hypertrophy and heart failure
-
批准号:nhmrc : 1007712
-
项目类别:NHMRC Project Grants
-
资助金额:$36.6万
-
财政年份:2011
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Research Fellowship
-
批准号:nhmrc : 586621
-
项目类别:NHMRC Research Fellowships
-
资助金额:$47.68万
-
财政年份:2010
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
A novel cardiac inotropic mechanism that provides functional benefit
-
批准号:nhmrc : 526622
-
项目类别:NHMRC Project Grants
-
资助金额:$27.6万
-
财政年份:2009
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Cardiac-specific therapy targeting hypertrophy and apoptotis
-
批准号:nhmrc : 526623
-
项目类别:NHMRC Project Grants
-
资助金额:$36.19万
-
财政年份:2009
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Regulation of cardiac hypertrophy a at the level of ribosome biogenesis
-
批准号:nhmrc : 508907
-
项目类别:NHMRC Project Grants
-
资助金额:$42.31万
-
财政年份:2008
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Signalling pathways activated by atrial dilatation and their relationship to atrial fibrillation
-
批准号:nhmrc : 418935
-
项目类别:NHMRC Project Grants
-
资助金额:$30.0万
-
财政年份:2007
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
FOXO proteins and protection from cardiac ischaemic injury
-
批准号:nhmrc : 317801
-
项目类别:NHMRC Project Grants
-
资助金额:$23.63万
-
财政年份:2005
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Ischaemia-induced sarcolemmal changes and their role in Ins(1,4,5)P3 generation and arrhythmogenesis
-
批准号:nhmrc : 317802
-
项目类别:NHMRC Project Grants
-
资助金额:$31.26万
-
财政年份:2005
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Research Fellowship - Grant ID:317803
-
批准号:nhmrc : 317803
-
项目类别:NHMRC Research Fellowships
-
资助金额:$43.46万
-
财政年份:2005
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
Inositol polyphosphate 1-phosphatase, a novel anti-hypertrophic factor
-
批准号:nhmrc : 268921
-
项目类别:NHMRC Project Grants
-
资助金额:$26.66万
-
财政年份:2004
-
负责人:A/Pr Elizabeth Woodcock
-
依托单位:
国内基金
海外基金
堆垒基与Narkiewicz常数的研究
-
批准号:11226279
-
项目类别:数学天元基金项目
-
资助金额:3.0万元
-
批准年份:2012
-
负责人:王庆红
-
依托单位: