Targeting oxidant-dependent pathways to improve stroke outcomes in COPD

针对氧化剂依赖性途径改善慢性阻塞性肺病的中风结果

• 批准号: nhmrc : 1120522
• 负责人: A/Pr Daniel Steinfort
• 金额: $ 73.05万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-oxidant-dependent-outcomes-copd/946558
• 关键词: Targeting; oxidant; dependent; pathways; improve

Chronic Obstructive Pulmonary Disease (COPD) is a major incurable global health burden and is the 4th largest cause of death worldwide. Patients with COPD are at increased risk for stroke and this is even higher in the weeks following a lung viral infection. The reason for this is unknown so the aim of this study is to determine why people with COPD are at increased risk for stroke and then develop novel treatments to prevent or reduce stroke in COPD patients.

慢性阻塞性肺疾病（COPD）是全球主要的无法治愈的健康负担，也是全球第四大死因。慢性阻塞性肺病患者中风的风险增加，在肺部病毒感染后的几周内这一风险甚至更高。其原因尚不清楚，因此本研究的目的是确定为什么慢性阻塞性肺病患者中风的风险增加，然后开发新的治疗方法来预防或减少慢性阻塞性肺病患者的中风。