靶向致病性 TAR DNA 结合蛋白 43 治疗额颞叶痴呆和运动神经元疾病-猫眼课题宝

靶向致病性 TAR DNA 结合蛋白 43 治疗额颞叶痴呆和运动神经元疾病

批准号：

nhmrc : 2001572

负责人：

金额：

$68.74万

依托单位：

依托单位国家：

澳大利亚

项目类别：

Ideas Grants

财政年份：

2021

资助国家：

澳大利亚

项目状态：

已结题

起止时间：

2021-01-01 至 2023-12-31

来源：

https://researchdata.edu.au/targeting-pathogenic-tar-neuron-disease/1779804

关键词：

Targeting pathogenic TAR DNA binding

中文摘要

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英文摘要

Frontotemporal dementia and motor neuron Disease are rapidly progressive and fatal neurodegenerative diseases that affect people in their prime. Poor understanding of the processes that lead to these diseases have slowed drug development. Through innovative experimental design, we aim to decipher a novel disease mechanism that involves specific molecular interactions and translate these findings into new therapies for the diseases.

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