The Ins and Outs of Endocytosis inhibition: Providing diverse opportunities for treatment of incurable cancers
The Ins and Outs of Endocytosis inhibition: Providing diverse opportunities for treatment of incurable cancers
批准号:
nhmrc : 2001396
负责人:
金额:
$91.24万
依托单位国家:
澳大利亚
项目类别:
Ideas Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2024-12-31
中文摘要
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英文摘要
The best new immune system anti-cancer drugs only work in ~30% of patients. We found a way to move the drug targets around in people's tumours temporarily to reverse resistance and have tested this in clinical trials. Here we propose to use immunology and the world's frontier electron microscope techniques to work out exactly what is happens to the tumours, immune cells and anti-cancer drugs when they interact in real clinical situations. The aim is to reach at least 60% patient response rate.
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