TORPIDO2- Targeted Oxygen for Resuscitation of Preterm Infants effects on Developmental Outcomes 2

TOPIDO2-早产儿复苏的定向氧气对发育结果的影响 2

• 批准号: nhmrc : 1089056
• 负责人: A/Pr Kei Lui
• 金额: $ 152.93万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/torpido2-targeted-oxygen-outcomes-2/519243
• 关键词: TORPIDO2; Targeted; Oxygen; Resuscitation; Preterm

Either too much or too little oxygen (O2) causes prolonged harm and death, even if this imbalance is for a few minutes, as at birth. Nowhere is this balance more critical than in the care of the extremely preterm infant (below 28 weeks gestation) with lung immaturity (requiring O2) and antioxidant deficiency. The Torpido 2 study will randomize 1350 infants below 28 weeks gestation to determine long-term neurodevelopmental outcomes and survival after resuscitation with either 21% O2 (room air) or

过多或过少的氧气（O2）会导致长期的伤害和死亡，即使这种不平衡只有几分钟，就像出生时一样。没有什么比照顾肺部不成熟（需要氧气）和抗氧化剂缺乏的极早产儿（妊娠28周以下）更重要的了。Torpido 2研究将随机选择1350名孕28周以下的婴儿，以确定21% O2（室内空气）或21% O2（室内空气）复苏后的长期神经发育结局和存活率。