Instantaneous deposition rate of aerosols in the lung

点击翻译按钮获取中文摘要

The coordination of aerosol drug delivery with the breathing pattern of individual patients is one of the greatest challenges in developing the next generation of smart aerosol delivery devices. Accurate numerical simulation of aerosol deposition is essential for the optimal design and development of these new devices. The presently existing deposition models cannot capture the effect of transient breathing pattern and cannot predict the time dependent local deposition rates. The goal of this project is to develop novel deposition functions for the instantaneous, transient deposition rate of aerosol particles.