Statistical mechanics of polymer systems and lipid bilayer membranes

我的研究主要集中在复杂流体的结构和动力学性质上，包括单链聚合物体系、朗缪尔单分子膜和脂类双层膜。这些聚合物系统在薄膜技术和环境应用方面有实际应用，例如在土壤修复过程中使用生物膜(这与UPEI在生态毒理学方面的专业知识很好地联系在一起)。此外，这项研究还具有重要的生物医学意义。例如，对溶液中孤立聚合物的卷曲-球体和球体-固体转变的研究对于深入了解主导蛋白质折叠过程的一些关键特征是必不可少的。在我提出的研究中，我将使用不连续分子动力学(DMD)模拟来研究不同参数，包括单体/溶剂尺寸比，对均聚和杂聚体系的崩溃和冻结转变的影响。

My research focuses on the structural and dynamical properties of complex fluids, including single-chain polymer systems, Langmuir monolayers, and lipid bilayer membranes. These polymeric systems have practical applications in thin-film technology and have environmental applications, such as employing biofilms in soil remediation processes (which links well with UPEI's expertise in ecotoxicology). Additionally, this research has vital biomedical implications. For example, studies on the coil-globule and globule-solid transitions for isolated polymers in solution are essential to obtain insight into some of the key features that dominate the protein folding process. In my proposed research, I will use discontinuous molecular dynamics (DMD) simulations to examine the effects of varying different parameters, including the monomer/solvent size ratio, on both the collapse and freezing transitions for homopolymer and heteropolymer systems.