Interactions and molecular organization in polymer surfactant systems

聚合物-表面活性剂对在许多化妆品和农产品以及油漆和药物配方中起着关键作用。高分子量聚合物和低分子量表面活性剂往往结合起来，以利用其独特的协同性能；例如，聚合物的机械性能和表面活性剂的自组装行为。然而，由于缺乏关于生物聚合物和非离子表面活性剂组合的信息，聚合物表面活性剂体系尚未充分开发用于生物医学和制药应用。迄今为止，大多数关于聚合物-表面活性剂体系的基础研究都包括带电表面活性剂（例如十二烷基硫酸钠），由于其安全性和毒性较差，在生物医学应用中的应用潜力有限。通过这种方式，选择合适的生物聚合物-非离子表面活性剂对用于生物医学应用通常是通过试错来进行的。

Polymer-surfactant pairs play a critical role in many cosmetic and agriculture products as well as paint and pharmaceutical formulations. The high molecular weight polymers and low molecular weight surfactants are often combined to take advantage of their unique and synergistic properties; for example, the mechanical properties of the polymer and self-assembly behavior of the surfactant. However, polymer-surfactant systems have not been fully exploited for use in biomedical and pharmaceutical applications due to the lack of information available on combinations of biopolymers and nonionic surfactants. To date, most of the fundamental studies on polymer-surfactant systems have included charged surfactants (e.g. sodium dodecyl sulfate) which have limited potential for use in biomedical applications due to their poor safety and toxicity profiles. In this way, the selection of appropriate biopolymer- nonionic surfactant pairs for biomedical applications often proceeds by trial and error.