new agents for the visualization of biochemistry in live cells
new agents for the visualization of biochemistry in live cells
批准号:
288338-2007
负责人:
Campbell, Robert
金额:
$4.01万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-01-01 至 2010-12-31
中文摘要
蛋白质是令人惊叹的分子机器,对我们所知的生命是必不可少的。经过一个世纪的蛋白质研究,我们现在对蛋白质如何能够执行其广泛的功能有了很好的理解。然而,我们的理解还不够深入,不足以让我们理性地设计具有自然界中没有的功能的新蛋白质结构。因此,当我们想要用蛋白质作为有益于人类的‘工具’时,我们受到大自然提供的东西的限制。幸运的是,大自然一直很慷慨,蛋白质“工具”现在在现代生活的许多方面都被视为理所当然,包括家用产品(例如洗衣粉)、医疗诊断(例如控制糖尿病的血糖传感器)和生物技术(例如聚合酶链式反应)。
英文摘要
Proteins are amazing molecular machines that are essential for Life as we know it. After a century of protein research, we now have a very good understanding of how proteins are able to carry out their vast array of functions. However, our understanding is not deep enough to allow us to rationally design new protein structures with functions not found in Nature. Thus, when we want to use proteins as benign 'tools' to benefit mankind, we are limited to what Nature has provided us. Fortunately, Nature has been generous and protein 'tools' are now taken for granted in many aspects of modern life, including household products (e.g. laundry detergent), medical diagnostics (e.g. blood glucose sensors to control diabetes), and biotechnology (e.g. PCR).
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会议论文
Engineering Protein Structure and Interactions to Create Next Generation Optogenetic Tools
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批准号:RGPIN-2018-04364
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项目类别:Discovery Grants Program - Individual
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资助金额:$17.63万
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财政年份:2022
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负责人:Campbell, Robert
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依托单位:
Engineering Protein Structure and Interactions to Create Next Generation Optogenetic Tools
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批准号:RGPIN-2018-04364
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项目类别:Discovery Grants Program - Individual
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资助金额:$8.81万
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财政年份:2021
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负责人:Campbell, Robert
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依托单位:
Engineering Protein Structure and Interactions to Create Next Generation Optogenetic Tools
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批准号:RGPIN-2018-04364
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项目类别:Discovery Grants Program - Individual
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资助金额:$8.81万
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财政年份:2020
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负责人:Campbell, Robert
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依托单位:
Engineering Protein Structure and Interactions to Create Next Generation Optogenetic Tools
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批准号:RGPIN-2018-04364
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项目类别:Discovery Grants Program - Individual
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资助金额:$8.81万
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财政年份:2019
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负责人:Campbell, Robert
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依托单位:
Engineering Protein Structure and Interactions to Create Next Generation Optogenetic Tools
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批准号:RGPIN-2018-04364
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项目类别:Discovery Grants Program - Individual
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资助金额:$8.81万
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财政年份:2018
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
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批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2017
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
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批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2016
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
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批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2015
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
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批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2014
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负责人:Campbell, Robert
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依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$1.82万
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财政年份:2014
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
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批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2013
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负责人:Campbell, Robert
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依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2013
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
-
批准号:288338-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.46万
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财政年份:2012
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负责人:Campbell, Robert
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依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2012
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负责人:Campbell, Robert
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依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2011
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负责人:Campbell, Robert
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依托单位:
A second generation screening system for fluorescence-guided protein engineering
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批准号:422242-2012
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$3.81万
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财政年份:2011
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负责人:Campbell, Robert
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依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
-
批准号:288338-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.46万
-
财政年份:2011
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负责人:Campbell, Robert
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依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$7.29万
-
财政年份:2010
-
负责人:Campbell, Robert
-
依托单位:
Moulding fluorescent proteins into biotools: engineering topology, surfaces and chromophores
-
批准号:288338-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$5.46万
-
财政年份:2010
-
负责人:Campbell, Robert
-
依托单位:
Bioanalytical Chemistry
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批准号:1000210802-2008
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项目类别:Canada Research Chairs
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资助金额:$5.46万
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财政年份:2009
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负责人:Campbell, Robert
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依托单位:
国内基金
海外基金
基于LLM的Agents决策偏差研究——从处置效应案例到机器行为主义
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批准号:--
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项目类别:青年科学基金项目
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资助金额:--
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批准年份:2024
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负责人:李春晓
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依托单位:
社会依赖演化网调控的Agent服务协同自适应
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批准号:61375071
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项目类别:面上项目
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资助金额:78.0万元
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批准年份:2013
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负责人:高济
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依托单位:
生物素-亲和素介导超声造影剂对乳腺癌血管生成分子靶向显像的研究
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批准号:30670580
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项目类别:面上项目
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资助金额:26.0万元
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批准年份:2006
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负责人:李颖嘉
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依托单位: