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Integrative strategies for metabolomic analyses by capillary electrophoresis

Integrative strategies for metabolomic analyses by capillary electrophoresis
毛细管电泳代谢组学分析的综合策略
批准号:
298422-2009
负责人:
BritzMcKibbin, Philip
金额:
$3.64万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-01-01 至 2010-12-31

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中文摘要
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英文摘要
Metabolomics represents an emerging field of functional genomic research that has promising applications in drug discovery and disease prognosis. Capillary electrophoresis (CE) offers a versatile format for metabolomic analyses, which can also be used to study protein-drug interactions in free solution. Our group is interested in developing fully integrated strategies for metabolomics which combine sample pretreatment with chemical analysis in a single-step. This offers the benefit of a rapid, automated and sensitive format for metabolite analysis not feasible by conventional chromatographic or spectroscopic techniques. The long-term goals of this research proposal address three major obstacles confronting current metabolomic initiatives.
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