Translation of glaucoma blindness genes to improve clinical practice
Translation of glaucoma blindness genes to improve clinical practice
批准号:
nhmrc : GNT1147571
负责人:
A/Pr Alex Hewitt
金额:
$84.5万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Glaucoma is a common cause of irreversible blindness. It is currently difficult to predict which patients with the earliest signs of glaucoma will develop blinding stages of the disease. This study will investigate how genes and eye measurements can be used to predict the risk of developing severe glaucoma in people with early signs of disease. This will ensure that high risk individuals can access treatment early, while those at low risk can be spared unnecessary treatment and seen less often.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Translating genetic determinants of glaucoma into better diagnosis and treatment
-
批准号:nhmrc : GNT1150144
-
项目类别:Programs
-
资助金额:$946.6万
-
财政年份:2019
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Translating genetic determinants of glaucoma into better diagnosis and treatment
-
批准号:nhmrc : 1150144
-
项目类别:Program Grants
-
资助金额:$631.19万
-
财政年份:2019
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Translation of glaucoma blindness genes to improve clinical practice
-
批准号:nhmrc : 1147571
-
项目类别:Project Grants
-
资助金额:$57.13万
-
财政年份:2018
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Self-destructing CRISPR-constructs for targeted genome editing in the retina.
-
批准号:nhmrc : 1123329
-
项目类别:Project Grants
-
资助金额:$46.45万
-
财政年份:2017
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Young adult myopia: genetic and environmental associations
-
批准号:nhmrc : 1121979
-
项目类别:Project Grants
-
资助金额:$55.27万
-
财政年份:2017
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Self-destructing CRISPR-constructs for targeted genome editing in the retina.
-
批准号:nhmrc : GNT1123329
-
项目类别:Project Grants
-
资助金额:$67.99万
-
财政年份:2017
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Young adult myopia: genetic and environmental associations
-
批准号:nhmrc : GNT1121979
-
项目类别:Project Grants
-
资助金额:$80.93万
-
财政年份:2017
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)
-
批准号:nhmrc : 1132454
-
项目类别:Partnerships
-
资助金额:$40.6万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Molecular profiling to identify therapeutic targets for blinding diseases.
-
批准号:nhmrc : GNT1103329
-
项目类别:Practitioner Fellowships
-
资助金额:$46.8万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
High penetrance deleterious mutations in blinding glaucoma
-
批准号:nhmrc : GNT1107098
-
项目类别:Project Grants
-
资助金额:$134.51万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)
-
批准号:nhmrc : GNT1132454
-
项目类别:Partnerships
-
资助金额:$59.54万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
From discovery to therapy in genetic eye diseases
-
批准号:nhmrc : GNT1116360
-
项目类别:Centres of Research Excellence
-
资助金额:$249.82万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
High penetrance deleterious mutations in blinding glaucoma
-
批准号:nhmrc : 1107098
-
项目类别:Project Grants
-
资助金额:$91.46万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Molecular profiling to identify therapeutic targets for blinding diseases.
-
批准号:nhmrc : 1103329
-
项目类别:Practitioner Fellowships
-
资助金额:$32.26万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
From discovery to therapy in genetic eye diseases
-
批准号:nhmrc : 1116360
-
项目类别:Centres of Research Excellence
-
资助金额:$170.68万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Dissecting the great ophthalmic masquerade: The Global Giant Cell Arteritis Genomics Consortium.
-
批准号:nhmrc : 1068023
-
项目类别:Project Grants
-
资助金额:$38.89万
-
财政年份:2014
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Genome-wide association studies to identify major genetic determinants of 5 blinding eye diseases using pooled DNA
-
批准号:nhmrc : 1031362
-
项目类别:Project Grants
-
资助金额:$37.49万
-
财政年份:2012
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Genetic etiologies of congenital esotropia
-
批准号:nhmrc : 1031920
-
项目类别:Project Grants
-
资助金额:$24.79万
-
财政年份:2012
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Genome-wide association study (GWAS) for juvenile-onset myopia and its component measures to identify molecular pathways to prevent myopia
-
批准号:nhmrc : 1021105
-
项目类别:Project Grants
-
资助金额:$33.03万
-
财政年份:2012
-
负责人:A/Pr Alex Hewitt
-
依托单位:
Translation of genetic eye research integrating education, counselling and testing with gene discovery and gene based therapies for eye disease
-
批准号:nhmrc : 1023911
-
项目类别:Centres of Research Excellence
-
资助金额:$178.69万
-
财政年份:2012
-
负责人:A/Pr Alex Hewitt
-
依托单位:
国内基金
海外基金
原发性开角型青光眼中SIPA1L1促进小梁网细胞外基质蛋白累积升高眼压的作用机制
-
批准号:82371054
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:郭涛
-
依托单位:
TXNIP调控实验性青光眼视乳头星形胶质细胞的激活及其机制研究
-
批准号:82371048
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:钟一声
-
依托单位: