Genome-wide association studies to identify major genetic determinants of 5 blinding eye diseases using pooled DNA
Genome-wide association studies to identify major genetic determinants of 5 blinding eye diseases using pooled DNA
批准号:
nhmrc : 1031362
负责人:
A/Pr Alex Hewitt
金额:
$37.49万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
This project aims to find important genes for 5 diseases that can lead to blindness. We will use a cost-effective approach where samples from a large number of individuals with a given disorder are pooled (mixed together) and then compared on gene chips covering the whole genome to a pool of people who do not have the disease. Differences identified between the groups will point to genes causing that disease. We will identify any major genes for the 5 diseases being studied.
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资助金额:$946.6万
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财政年份:2019
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负责人:A/Pr Alex Hewitt
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依托单位:
Translating genetic determinants of glaucoma into better diagnosis and treatment
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负责人:A/Pr Alex Hewitt
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依托单位:
Translation of glaucoma blindness genes to improve clinical practice
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负责人:A/Pr Alex Hewitt
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依托单位:
Self-destructing CRISPR-constructs for targeted genome editing in the retina.
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批准号:nhmrc : 1123329
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项目类别:Project Grants
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资助金额:$46.45万
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财政年份:2017
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负责人:A/Pr Alex Hewitt
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依托单位:
Young adult myopia: genetic and environmental associations
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批准号:nhmrc : 1121979
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资助金额:$55.27万
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财政年份:2017
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负责人:A/Pr Alex Hewitt
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依托单位:
Self-destructing CRISPR-constructs for targeted genome editing in the retina.
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批准号:nhmrc : GNT1123329
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项目类别:Project Grants
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资助金额:$67.99万
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财政年份:2017
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负责人:A/Pr Alex Hewitt
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依托单位:
Young adult myopia: genetic and environmental associations
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批准号:nhmrc : GNT1121979
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资助金额:$80.93万
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财政年份:2017
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负责人:A/Pr Alex Hewitt
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依托单位:
Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)
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资助金额:$40.6万
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负责人:A/Pr Alex Hewitt
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依托单位:
Molecular profiling to identify therapeutic targets for blinding diseases.
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批准号:nhmrc : GNT1103329
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项目类别:Practitioner Fellowships
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资助金额:$46.8万
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财政年份:2016
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负责人:A/Pr Alex Hewitt
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依托单位:
High penetrance deleterious mutations in blinding glaucoma
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项目类别:Project Grants
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资助金额:$134.51万
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财政年份:2016
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负责人:A/Pr Alex Hewitt
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依托单位:
Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)
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项目类别:Partnerships
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财政年份:2016
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负责人:A/Pr Alex Hewitt
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依托单位:
From discovery to therapy in genetic eye diseases
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资助金额:$249.82万
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财政年份:2016
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负责人:A/Pr Alex Hewitt
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依托单位:
High penetrance deleterious mutations in blinding glaucoma
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批准号:nhmrc : 1107098
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项目类别:Project Grants
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资助金额:$91.46万
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财政年份:2016
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负责人:A/Pr Alex Hewitt
-
依托单位:
Molecular profiling to identify therapeutic targets for blinding diseases.
-
批准号:nhmrc : 1103329
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项目类别:Practitioner Fellowships
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资助金额:$32.26万
-
财政年份:2016
-
负责人:A/Pr Alex Hewitt
-
依托单位:
From discovery to therapy in genetic eye diseases
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批准号:nhmrc : 1116360
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项目类别:Centres of Research Excellence
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资助金额:$170.68万
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财政年份:2016
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负责人:A/Pr Alex Hewitt
-
依托单位:
Dissecting the great ophthalmic masquerade: The Global Giant Cell Arteritis Genomics Consortium.
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批准号:nhmrc : 1068023
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项目类别:Project Grants
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资助金额:$38.89万
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财政年份:2014
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负责人:A/Pr Alex Hewitt
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依托单位:
Genetic etiologies of congenital esotropia
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批准号:nhmrc : 1031920
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项目类别:Project Grants
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资助金额:$24.79万
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财政年份:2012
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负责人:A/Pr Alex Hewitt
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依托单位:
Genome-wide association study (GWAS) for juvenile-onset myopia and its component measures to identify molecular pathways to prevent myopia
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批准号:nhmrc : 1021105
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项目类别:Project Grants
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资助金额:$33.03万
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财政年份:2012
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负责人:A/Pr Alex Hewitt
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依托单位:
Translation of genetic eye research integrating education, counselling and testing with gene discovery and gene based therapies for eye disease
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批准号:nhmrc : 1023911
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项目类别:Centres of Research Excellence
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资助金额:$178.69万
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财政年份:2012
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负责人:A/Pr Alex Hewitt
-
依托单位:
国内基金
海外基金
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