Understanding the clinical significance of tumour genomic architecture and host immune response in breast cancer.

了解乳腺癌中肿瘤基因组结构和宿主免疫反应的临床意义。

• 批准号: nhmrc : GNT1094388
• 负责人: Dr Peter Savas
• 金额: $ 8.06万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-clinical-significance-breast-cancer/1345947
• 关键词: Understanding; clinical; significance; tumour; genomic

This study uses sophisticated DNA sequencing technologies to help patients and their doctors better understand and treat breast cancer. It also tries to understand how the cancer DNA may change over time, and if this is important to how the cancer is treated. In addition, it looks for a link between the DNA changes in a tumour and the anti-tumour immune response, which may help identify patients that could benefit from immunotherapy in the future.

这项研究使用复杂的DNA测序技术来帮助患者和他们的医生更好地了解和治疗乳腺癌。它还试图了解癌症DNA如何随时间变化，以及这对如何治疗癌症是否重要。此外，它还寻找肿瘤中DNA变化与抗肿瘤免疫反应之间的联系，这可能有助于确定未来可能从免疫治疗中受益的患者。