Understanding how group 2 innate lymphoid cells in early life regulate postnatal lung development and susceptibility to chronic respiratory diseases

了解生命早期第 2 组先天淋巴细胞如何调节出生后肺部发育和对慢性呼吸道疾病的易感性

• 批准号: nhmrc : GNT1156898
• 金额: $ 50.1万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-group-2-respiratory-diseases/1378965
• 关键词: Understanding; how; group; innate; lymphoid

Impaired lung growth that results from respiratory infections in early life negatively impacts on respiratory health and may lead to the development of asthma and emphysema. The identification and exploitation of the factors that promote normal healthy lung development may lead to new strategies to prevent and treat respiratory diseases. We have identified a new type of cell that we think are critical for lung development. This may have substantial health and economic benefits in the future.

早期呼吸道感染导致的肺部生长受损对呼吸系统健康产生负面影响，并可能导致哮喘和肺气肿的发展。识别和利用促进正常健康肺发育的因素可能会导致预防和治疗呼吸系统疾病的新策略。我们已经发现了一种新的细胞类型，我们认为它对肺部发育至关重要。这在未来可能会带来巨大的健康和经济效益。