Understanding the interplay between the gut-kidney axis in people with chronic kidney disease

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In chronic kidney disease (CKD), uremic toxins are believed to alter the biochemical setting, causing trouble in gut microbiota and intestinal barrier. 30% of transplant recipients experience gastrointestinal (GI) intolerance. We aim to understand the role of gut microbial biomarkers, food, and probiotics, for predicting progression of CKD; describe patient experiences; and discover the relationship between GI symptoms, faecal microbial diversity, and bacteria in kidney transplant and dialysis.