Understanding the key attributes of CD8 T cell receptor transfer as an antiviral strategy and harnessing the process to combat persistent viral infections
Understanding the key attributes of CD8 T cell receptor transfer as an antiviral strategy and harnessing the process to combat persistent viral infections
批准号:
nhmrc : 1007980
负责人:
A/Pr Gunasegaran Karupiah
金额:
$40.87万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31
中文摘要
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英文摘要
We have recently discovered a new process through which the numbers of antiviral immune cells can rapidly expand, without dividing, to combat a virus infection that may otherwise be fatal. This represents a significant advance in our knowledge on how a speedy, virus-specific response can be mounted. We will study how this process can be applied to therapeutic strategies to overcome medically significant persistent viral infections.
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依托单位:
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Role of plasmacytoid dendritic cells and neutrophils in the generation of antiviral immunity
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依托单位:
Critical role of TNF in host-virus interactions and outcome of infection: Involvement of reverse signalling through mTNF
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依托单位:
Pathophysiological significance of reverse signaling through membrane TNF
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依托单位:
Role of nitric oxide in influenza A virus-induced pneumonia
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