Understanding the role of light exposure in individual differences in the circadian response to shift work

这项研究将评估环境光暴露对夜班工人昼夜节律起搏器反应的影响。它将改进一种新的昼夜节律起搏器的生物数学模型，以提高对个别轮班工人的昼夜节律的预测。这一预测将提供个性化的建议，以加强昼夜轮班的适应，并减少昼夜节律失调对健康和安全的负面影响。

This study will evaluate the effects of environmental light exposure on the response of the circadian pacemaker to night shift in a large sample of shift workers. It will refine a novel biomathematical model of the circadian pacemaker to improve predictions of circadian timing for individual shift workers. This prediction will inform personalised recommendations to enhance circadian adaptation to night shift and reduce the negative implications of circadian misalignment on health and safety.