Understanding the role of light exposure in individual differences in the circadian response to shift work

了解光照在轮班工作昼夜节律反应个体差异中的作用

• 批准号: nhmrc : 2001234
• 金额: $ 80.37万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-role-light-shift-work/1779738
• 关键词: Understanding; role; light; exposure; individual

This study will evaluate the effects of environmental light exposure on the response of the circadian pacemaker to night shift in a large sample of shift workers. It will refine a novel biomathematical model of the circadian pacemaker to improve predictions of circadian timing for individual shift workers. This prediction will inform personalised recommendations to enhance circadian adaptation to night shift and reduce the negative implications of circadian misalignment on health and safety.

本研究将在大样本的轮班工人中评估环境光暴露对昼夜节律起搏器对夜班反应的影响。它将完善一个新的生物节律起搏器的生物数学模型，以提高个人轮班工人的昼夜节律时间的预测。这一预测将为个性化建议提供信息，以增强昼夜节律对夜班的适应，并减少昼夜节律失调对健康和安全的负面影响。