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Unique and selective small molecules to dissect histone acetyltransferase biology

Unique and selective small molecules to dissect histone acetyltransferase biology
独特且选择性的小分子可剖析组蛋白乙酰转移酶生物学
批准号:
nhmrc : 1080146
负责人:
A/Pr Tim Thomas
金额:
$46.29万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31

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中文摘要
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英文摘要
A class of enzymes called histone acetyltransferases appear to be important in a variety of diseases, from inflammation to cancer. We are developing potent and selective compounds that will be able to tell us which of these enzymes may be targets for cancer, and which for inflammatory disorders. This will be invaluable for better treatment of debilitating human diseases with unmet needs.
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Unique and selective small molecules to dissect histone acetyltransferase biology
  • 批准号:
    nhmrc : GNT1080146
  • 项目类别:
    Project Grants
  • 资助金额:
    $67.25万
  • 财政年份:
    2015
  • 负责人:
    A/Pr Tim Thomas
  • 依托单位:
Genetic regulation of mammlian development
The role of the MYST family lysine acetyltransferase, Hbo1, in development and in the adult
Role of chromatin structure in the regulation of stem cell function
  • 批准号:
    nhmrc : 171600
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $18.14万
  • 财政年份:
    2001
  • 负责人:
    A/Pr Tim Thomas
  • 依托单位:
国内基金
海外基金
新型M4受体选择性拮抗剂的研究