A system for protein purification

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The Christendat lab uses structural, enzymological and biochemical approaches to investigate enzymes of the shikimate pathway in plants and microbes. There are two major themes being investigated in the lab: 1) The mechanism by which the pathway enzymes are regulated in plants and 2) the evolutionary relationship of the shikimate pathway enzymes in plants and microbes. The results from these two themes will contribute to a better understanding of the shikimate pahway which could eventually facilitate metabolic engineering of crops to enhance their nutritional contents and also facilitate the development of novel antimicrobial and herbicidal agents. This protein purification system requested would enhance our ability to prepare high quality proteins, which are essential for our research program.