Vascular targeting combined with radiosurgery in an arteriovenous malformation rat model

血管靶向联合放射外科治疗动静脉畸形大鼠模型

• 批准号: nhmrc : 1115183
• 金额: $ 7.01万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/vascular-targeting-combined-rat-model/663366
• 关键词: Vascular; targeting; combined; radiosurgery; arteriovenous

Cerebral arteriovenous malformations are an important cause of stroke and brain bleeds. In many patients such a stroke can result in severe disability or death. Current management involves a combination of surgery, radiation therapy and endovascular treatments and carry a high risk of complications. This research project suggests a new form of treatment whereby irradiating the vascular malformation a medication could be administered to cause targeted clotting of the malformation.

脑动静脉畸形是中风和脑出血的重要原因。对于许多患者来说，这种中风可能导致严重残疾或死亡。目前的治疗方法包括手术、放射治疗和血管内治疗相结合，并且并发症的风险很高。该研究项目提出了一种新的治疗方法，通过照射药物可以引起血管畸形的靶向凝血。