Nuclear receptors and the integrative metabolism of boar taint compounds

核受体和公猪异味化合物的综合代谢

• 批准号: 36486-2007
• 负责人: Squires, EliJames(Jim)
• 金额: $ 2.99万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=450626
• 关键词: Nuclear; receptors; integrative; metabolism; boar

This research is designed to obtain a more complete understanding of factors affecting the accumulation of odorous compounds, skatole (3-methylindole) and the 16-androstene steroids (especially androstenone), in pigs. These compounds cause undesirable off-odors and off-flavors (boar taint) in pork meat produced from uncastrated male pigs. The 16-androstene steroids are produced by the testis near maturity and act as sex pheromones, while skatole is produced by bacteria in the gut and contributes to the characteristic odour of pig manure. Male pigs are routinely castrated at an early age to prevent boar taint, but castration raises concerns about animal welfare, as well as decreases the growth efficiency and lean yield of the pigs.

本研究旨在更全面地了解影响猪体内恶臭化合物、粪臭素（3-甲基吲哚）和16-雄甾烯类固醇（特别是雄甾烯酮）积累的因素。这些化合物在由未阉割的雄性猪生产的猪肉中引起不期望的异味和异味（野猪味）。16-雄甾烯类固醇是由接近成熟的睾丸产生的，并作为性信息素，而粪臭素是由肠道中的细菌产生的，并导致了猪粪便的特征气味。雄性猪通常在很小的时候就被阉割，以防止公猪的污点，但阉割引起了对动物福利的担忧，并降低了猪的生长效率和瘦肉产量。