Vasoactive nutrients to promote healthy ageing in postmenopausal women

血管活性营养素促进绝经后女性健康衰老

• 批准号: nhmrc : 1106170
• 金额: $ 41.03万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/vasoactive-nutrients-promote-postmenopausal-women/662889
• 关键词: Vasoactive; nutrients; promote; healthy; ageing

Poor circulatory function in the brain, associated with mood and cognitive disturbances, can be further exacerbated by ageing and estrogen deprivation at postmenopause. My research will determine whether phytoestrogen supplementation with either resveratrol or genistein for 2 years can counteract menopause-related impairments in mood and mental performance by enhancing cerebral vasodilator function and whether the magnitude of improvement differs between early and late menopausal years.

与情绪和认知障碍相关的大脑循环功能低下，可能会因年龄增长和绝经后雌激素缺乏而进一步恶化。我的研究将确定植物雌激素补充剂与白藜芦醇或染料木黄酮2年是否可以通过增强脑血管舒张功能来抵消更年期相关的情绪和精神表现障碍，以及改善的幅度是否在绝经早期和晚期之间存在差异。