Dynamics in molecular and cellular control systems

分子和细胞控制系统的动力学

• 批准号: 36920-2008
• 负责人: Mackey, Michael
• 金额: $ 4.55万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=450703
• 关键词: Dynamics; molecular; cellular; control; systems

This research is a combined exploration of cellular and molecular dynamics using sophisticated mathematical modeling in conjunction with laboratory data to understand observed biological dynamics. The systems to be studied include the regulation of apoptosis (programmed cellular death) in mammalian cells, the development of pattern in the mammalian embryo, and the dynamics of the regulation of the tryptophan operon in bacteria.

这项研究是对细胞和分子动力学的综合探索，使用复杂的数学模型结合实验室数据来了解观察到的生物动力学。将要研究的系统包括哺乳动物细胞的凋亡(程序性细胞死亡)的调控，哺乳动物胚胎的模式发育，以及细菌中色氨酸操纵子的调控动力学。