In vivo evaluation of the safety and efficacy of a novel chitosan gel in the reduction of adhesions following abdominal surgery in both animal and human models

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Up to 95% of abdominal surgery patients will develop adhesions within the abdomen, with nearly 1 in 5 requiring hospital readmission for pain, reduced gastrointestinal function and bowel obstruction. Newly developed Chitodex gel has been shown to be effective in the control of bleeding and the reduction of adhesions following sinus surgery. These projects will now explore its use in abdominal surgery. Chitodex gel has the potential to benefit millions of patients each year and drastically lessen the burden on our health system.