Presynaptic contributions in synaptic plasticity

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Communication between cells is the core issue of biological science. In the brain, communication takes place at a specialized structure named the synapse. In addition to functioning as an information gateway between brain cells, it is well known that the strength of synapses can undergo long-term changes in an experience-dependent manner. This plastic property of synapse, which is termed as synaptic plasticity, is the cellular model for learning and memory. Thus, understanding the biological mechanisms of synaptic plasticity will greatly advance our knowledge of how memory is formed in the brain.