Discovery Projects - Grant ID: DP210101398

提高阶梯式楔形试验的效率和可解释性。阶梯形聚类随机试验越来越多地被用于测试许多学科的干预措施。该项目旨在开发高效的试验设计和新方法，以估计在不完全遵守干预措施时的因果可解释效应。该项目希望产生新的设计类型，减少测试干预措施所需的资源，以及了解这些干预措施如何工作的方法。预期的结果包括帮助研究人员开发更便宜、更吸引人的试验的工具、估计因果效应的工具、支撑这些工具的方法以及新的合作。这将使更多的干预措施得到测试和理解，从而带来显著的好处。

Increasing the efficiency and interpretability of stepped wedge trials. Stepped wedge cluster randomised trials are increasingly being used to test interventions, across many disciplines. This project aims to develop highly efficient trial designs and new methods for the estimation of causally interpretable effects when adherence to interventions is not perfect. This project expects to generate new design types that reduce resources required to test interventions, and methods to understand how these interventions work. Expected outcomes include tools to help researchers develop cheaper and more appealing trials, tools to estimate causal effects, the methodology underpinning these tools, and new collaborations. This should provide significant benefits by allowing more interventions to be tested and understood.