Jet mechanics of needle-free injection devices for swine

猪用无针注射装置的喷射力学

• 批准号: 401384-2010
• 负责人: Mann, Daniel
• 金额: $ 0.47万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=471351
• 关键词: Jet; mechanics; needle; free; injection

The mechanism of jet penetration into swine tissue from needle-free injection devices is not well understood. Previous research has investigated human devices, but they require a much lower injection pressure and dosage than devices used for animal injections. The objective of this research is to investigate the injection distribution that can be achieved by a needle-free injection device developed for swine in terms of depth of penetration and horizontal dispersion. Injection will be photographed using a high-speed camera to enable visualization of the dispersion. To enable photography, injections will be made into ballistic gelatine which is transparent and has previously been shown to have characteristics similar to tissue. Observing how the injectate travels through skin tissue is important in gauging the effectiveness of needle-free injection devices and achieving a more complete understanding of the affect on animal health.

无针注射装置喷射穿透猪组织的机理尚不清楚。之前的研究已经对人体设备进行了研究，但它们需要的注射压力和剂量比用于动物注射的设备低得多。本研究的目的是研究为猪研制的无针注射装置在渗透深度和水平分散方面可以实现的注射分布。注射将使用高速相机拍摄，以实现分散的可视化。为了能够拍照，注射将被制成弹道明胶，这种明胶是透明的，以前被证明具有与组织相似的特征。观察注射剂是如何在皮肤组织中流动的，对于衡量无针注射装置的有效性和更全面地了解对动物健康的影响非常重要。