Tangential flow fractionation system for capturing natural and manufactured nanoparticles

用于捕获天然和人造纳米颗粒的切向流分馏系统

• 批准号: 407828-2011
• 负责人: Jamieson, Heather
• 金额: $ 7.61万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=472728
• 关键词: Tangential; flow; fractionation; system; capturing

This is an application for filtration equipment will be used to capture nanoparticles and a centrifuge that is needed to prepare the samples for microanalysis. The tangential flow unit is a gentle method of extracting nanoparticles without changing them. It provides an accurate method of measuring the quantity of nanoparticles in a sample because the membranes that capture the particles do not get clogged as they do with other types of filtration. The solution flows across a relatively large filter membrane with a pore size that will prevent any particles greater than the desired size from passing through. Since the flud is pumped across rather than directly through the membrane, the larger particles do not accumulate on the membrane surface and clog it. Instead, they are swept away by the tangential, or cross flow.The second item requested is a centrifuge required to separate the solution from the particles retained on the membrane surface. This is needed so that the particles can be examined using an electron microscope to determine their amount and nature.

这是一个过滤设备的应用，将用于捕获纳米颗粒和离心机，需要准备样品进行微量分析。切向流动单元是一种不改变纳米颗粒的温和提取方法。它提供了一种精确的方法来测量样品中纳米颗粒的数量，因为捕获颗粒的膜不会像其他类型的过滤那样堵塞。溶液流过一个相对较大的过滤膜，该过滤膜的孔径可以防止任何大于所需尺寸的颗粒通过。由于流体是被泵送穿过膜而不是直接穿过膜，较大的颗粒不会积聚在膜表面并堵塞膜。相反，它们被切向流或横流冲走。要求的第二件物品是一台离心机，用于将溶液与保留在膜表面的颗粒分离。这是必要的，这样就可以用电子显微镜检查粒子，以确定它们的数量和性质。