Integrating ionic regulation, acid-base balance and cardiorespiratory function in fish

整合鱼类的离子调节、酸碱平衡和心肺功能

• 批准号: 38050-2007
• 负责人: Perry, Steve
• 金额: $ 6.6万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=474794
• 关键词: Integrating; ionic; regulation; acid; base

1. Much of my research examines how fish are able to adapt to changing environmental conditions and acute or chronic stressors. A large component of this application will address the involvement of an important hormonal response to stress, the adrenergic stress response. This response, aimed at optimising physiological function and minimising the detrimental effects of stress, is initiated by the release of two hormones into the bloodstream. These hormones, adrenaline and noradrenaline, are termed the catecholamine hormones. Specific research that is proposed in this grant application would attempt to elucidate the complex mechanisms triggering the release of catecholamines, a process that is presently not well understood in fish. This research is particularly relevant as fish continue to encounter deteriorating and stressful environmental conditions.

1. 我的大部分研究都考察了鱼类如何适应不断变化的环境条件以及急性或慢性压力源。 该应用程序的一个重要组成部分将涉及对压力的重要激素反应，即肾上腺素能应激反应。 这种反应旨在优化生理功能并最大限度地减少压力的有害影响，是由两种激素释放到血液中引发的。这些激素，肾上腺素和去甲肾上腺素，被称为儿茶酚胺激素。 本次拨款申请中提出的具体研究将试图阐明触发儿茶酚胺释放的复杂机制，这一过程目前在鱼类中尚不清楚。 随着鱼类继续面临不断恶化和充满压力的环境条件，这项研究尤其重要。