Integrating ionic regulation, acid-base balance and cardiorespiratory function in fish

整合鱼类的离子调节、酸碱平衡和心肺功能

• 批准号: RGPIN-2017-05545
• 负责人: Perry, Steve
• 金额: $ 6.56万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630442
• 关键词: Integrating; ionic; regulation; acid; base

My research seeks to understand how physiological systems promote optimal function in diverse environments. The overarching approach is to harness the power of modern biomedical techniques to address questions about the fundamental physiology of fish that, increasingly, are experiencing environmental perturbation. I see a need to address profoundly important but simple questions – how do animals sense their surroundings and how is this sensory information transformed into adaptive physiological responses? The short-term objectives build on current research and are centred on two areas; 1) mechanisms of chemoreception and ensuing cardiorespiratory responses and 2) mechanisms of ionic and acid-base regulation. The innovative new theme linking these areas is the metabolic cost of homeostasis.

我的研究旨在了解生理系统如何在不同的环境中促进最佳功能。总体方法是利用现代生物医学技术的力量来解决有关鱼类基本生理学的问题，这些问题越来越多地受到环境干扰。我认为有必要解决非常重要但简单的问题-动物如何感知周围环境，以及这种感官信息如何转化为适应性生理反应？短期目标建立在目前的研究基础上，集中在两个领域：1）化学感受机制和随后的心肺反应，2）离子和酸碱调节机制。连接这些领域的创新性新主题是稳态的代谢成本。