Australian Laureate Fellowships - Grant ID: FL210100099

智能显微镜-新颖的光学成像深度。虽然用于成像的光学方法被广泛使用，但通过具有高分辨率和深度的散射介质实现宽视场成像是一个重大挑战，这主要是由于光的穿透深度有限。该提案旨在通过能够捕获3D体积图像的新型智能显微镜来改变宽视场光学成像。在空间和时间上塑造光的创新将以整体的方式与计算分析相结合，以非凡的细节水平从样本深处提取图像。该研究的主要好处包括用于增强生物和物理材料发现的下一代工具，以及用于新成像和显微镜设备的新澳大利亚初创企业。

The Intelligent Microscope - novel optical imaging at depth. While optical methods for imaging are used extensively, achieving wide-field imaging through scattering media with high resolution and depth is a major challenge, due mainly to the limited penetration depth of light. This proposal aims to transform wide-field optical imaging through a new ‘intelligent’ microscopy able to capture 3D volumetric images. Innovations in shaping light in both space and time will be combined in a holistic way with computational analysis to extract images from deep within the sample at extraordinary levels of detail. Major benefits of the research range from next-generation tools for enhanced discovery of biological and physical materials, to new Australian start-ups for new imaging and microscopy devices.