Chemotherapy-induced peripheral neuropathy in the pediatric population: risk factors, assessment strategies and functional outcomes

儿科人群化疗引起的周围神经病变：危险因素、评估策略和功能结果

• 批准号: nhmrc : GNT1114801
• 负责人: Dr Tejaswi Kandula
• 金额: $ 8.88万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/chemotherapy-induced-peripheral-functional-outcomes/1346927
• 关键词: Chemotherapy; induced; peripheral; neuropathy; pediatric

Chemotherapy, commonly used for treatment of childhood cancer, can cause peripheral nerve injury with disabling symptoms which may be long lasting. This project aims to provide a comprehensive evaluation of the nerve injury and standardize sensitive ways of measuring nerve function. This is the first study that will follow children throughout their treatment cycle with regular nerve assessments, providing a greater understanding of nerve injury mechanisms and enabling treatment modification.

化疗通常用于治疗儿童癌症，可导致周围神经损伤，并有可能持续很长时间的致残症状。该项目旨在提供对神经损伤的综合评估，并标准化神经功能的敏感测量方法。这是第一项将在整个治疗周期中对儿童进行定期神经评估的研究，提供了对神经损伤机制的更多了解，并使治疗改进成为可能。