Response of Proteins to External Non-Ionising Radiation: an Experimental and Computer Modelling Investigation

蛋白质对外部非电离辐射的响应：实验和计算机建模研究

• 批准号: ARC : LP0219406
• 负责人: David McKenzie
• 金额: $ 25万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/response-proteins-external-modelling-investigation/73570
• 关键词: Response; Proteins; External; Non; Ionising

Response of Proteins to External Non-Ionising Radiation: an Experimental and Computer Modelling Investigation. The expanding use of digital technologies such as mobile phones has led to major health concerns about the effects of non-ionising pulsed radiation exposure which has been shown to produce instantaneous temperature rises undetectable by normal thermometry. The health implications of exposure are not understandable without establishing molecular mechanisms by which pulsed microwaves can cause biological effects. We aim to establish methods for studying the molecular mechanisms of protein structural and energetic changes occurring due to non-ionising radiation. The results will help our industry partner to design specific drugs as well as formulate a scientifically based standard for microwave utilisation.

蛋白质对外部非电离辐射的响应：实验和计算机建模研究。移动电话等数字技术的广泛使用引发了人们对非电离脉冲辐射暴露影响的重大健康担忧，这种辐射已被证明会产生正常测温无法检测到的瞬时温度升高。如果不建立脉冲微波引起生物效应的分子机制，就无法理解暴露对健康的影响。我们的目标是建立研究非电离辐射引起的蛋白质结构和能量变化的分子机制的方法。研究结果将帮助我们的行业合作伙伴设计特定药物以及制定基于科学的微波利用标准。