Synthesis of substrate analogues for probing catalytic mechanisms and specificity of enzymes involved in the metabolism of plant polysaccharides

底物类似物的合成，用于探索参与植物多糖代谢的酶的催化机制和专一性。该项目旨在加强阿德莱德和法国研究小组之间的合作，具体目标是合成底物类似物，作为大麦多糖水解酶和合成酶的酶机理和底物专一性的探针。化学专业知识驻留在法国，而酶学工作将主要在澳大利亚进行。研究人员的交流，特别是研究生和研究助理人员的交流，被认为是获取互补专门知识的好处和扩大现有国际合作的关键。在高等植物发育过程中，靶酶在细胞壁代谢中起着核心作用。

Synthesis of substrate analogues for probing catalytic mechanisms and specificity of enzymes involved in the metabolism of plant polysaccharides. The project is aimed at strengthening collaborations between research groups in Adelaide and France, with the specific objective of synthesizing substrate analogues as probes of enzymatic mechanisms and substrate specificity in polysaccharide hydrolases and synthases of barley. The chemical expertise resides in France, while the enzymatic work will be conducted largely in Australia. Exchange of research staff, particularly at the postgraduate student and research associate levels, is considered essential to capture the benefits of the complementary expertise and to extend an existing international collaboration. The target enzymes are of central importance in cell wall metabolism during development of higher plants.