Synthetic Molybdenum Enzymes

合成钼酶

• 批准号: ARC : DP0209007
• 负责人: A/Prof Charles Young
• 金额: $ 16.6万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/synthetic-molybdenum-enzymes/67591
• 关键词: Synthetic; Molybdenum; Enzymes

Synthetic Molybdenum Enzymes. This project aims to produce synthetic molybdenum (Mo) enzymes, small molecules that share structural and functional attributes with the crucially important molybdopterin?Mo enzymes. These ubiquitous enzymes are essential for plant and animal health, natural cycles involving carbon, nitrogen and sulfur, and global climate control and atmospheric albedo (reflectance); consequently, they impact heavily on commerce, the environment and society. The study will provide urgently needed insights into the fundamental Mo?sulfur chemistry of the enzyme active sites and inform efforts to reduce the negative impacts of enzyme dysfunction and the design of new commercial catalysts.

合成钼酶。该项目旨在生产合成钼（Mo）酶，这是一种小分子，与至关重要的钼酸盐具有相同的结构和功能属性。密苏里州的酶。这些无处不在的酶对动植物健康、涉及碳、氮和硫的自然循环以及全球气候控制和大气反照率（反射率）至关重要；因此，它们对商业、环境和社会产生了重大影响。这项研究将提供迫切需要的关于基本Mo？硫化学的酶活性位点，并告知努力减少酶功能障碍的负面影响和新的商业催化剂的设计。