New Frontiers in Molybdenum Chemistry: Electronic Structure and Molybdoenzyme Function

钼化学新前沿：电子结构和钼酶功能

• 批准号: DP0986311
• 负责人: A/Prof Charles Young
• 金额: $ 25.26万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0986311
• 关键词: New; Frontiers; Molybdenum; Chemistry; Electronic

Molybdenum enzymes play key roles in biology and environmental, biogeochemical and meteorological processes. This international, multidisciplinary project will employ advanced synthetic, instrumental and theoretical techniques to establish the link between electronic structures and molybdenum enzyme behaviour and function. The insights gained will inform the continuing development of agricultural, veterinary and medical treatments for diseases associated with enzyme dysfunction; these outcomes would be of enormous economic and societal benefit to Australia. The training of skilled scientists, access to advanced overseas facilities, and international recognition of Australian research, are important immediate benefits of the project.

钼酶在生物、环境、生物地球化学和气象过程中发挥着重要作用。这个国际性的多学科项目将采用先进的合成、仪器和理论技术来建立电子结构与钼酶行为和功能之间的联系。所获得的见解将为与酶功能障碍有关的疾病的农业、兽医和医学治疗的持续发展提供信息；这些成果将为澳大利亚带来巨大的经济和社会效益。培训技术娴熟的科学家，获得先进的海外设施，以及国际上对澳大利亚研究的认可，都是该项目的重要直接效益。